We are seeking driven, creative, and entrepreneurial individuals to help shape our company. At Alpha-9, you’ll find a culture of collaboration, transparency, and innovation. We are passionate about developing new medicines to help people living with cancer, and we are looking to add to our growing team.

Open Positions

Senior Scientist, Chemistry, Peptides

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking Senior Scientists to join our Chemistry group.  The ideal candidate will have hands-on experience in synthetic organic chemistry, including in the synthesis, isolation and purification of either small molecules, peptides or peptidomimetics. This person will be responsible for synthesizing peptides/peptidomimetic building blocks and precursors for radiopharmaceutical product candidates. Expertise in solid-phase peptide synthesis and the optimization of peptide ligands required.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Design and synthesis of peptides/peptidomimetics or small molecule-based building blocks and drug substances for radiopharmaceutical development
  • Working closely cross-functionally to achieve project goals
  • Supervision and mentoring of junior scientists
  • Compound characterization employing LC-MS/MS, GC-MS, HPLC and NMR
  • Lead project discussions and present results in team meetings
  • Key participant in the writing of patent applications
  • Maintenance of clear and accurate lab records, adherence to all safety and compliance requirements

Qualifications

  • PhD in Chemistry or related area with 5+ years of relevant industrial drug discovery experience
  • Solid understanding and practical experience in peptide drug discovery
  • Solid experience in modern synthetic and analytical techniques
  • Excellent observational, organizational, data management, and documentation skills

What’s in it for you

  • Full extended health benefits
  • Competitive salary, annual bonus, and equity
  • 20 vacation days
  • 17 holidays
  • 5 sick days
  • Group Registered Retirement Savings Plan with 5% employer match
  • Commuter reimbursement
  • Long term disability
  • Life insurance
  • Impactful and rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Animal Technician

About Us:

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary:

Alpha-9 is seeking a team-oriented Animal Research Technician to join the Translational Biology group within our growing organization. The ideal candidate will have experience in providing technical in vivo support for our research programs, preferably with radioactive substances. This person will be responsible for laboratory animal care and well-being, in addition to conducting in vivo research experiments with our experimental radiopharmaceuticals.

As a start-up organization, we value team members eager to make an impact and grow with us professionally.  We are seeking an individual who enjoys multi-tasking and has the willingness and flexibility to assume additional responsibilities as they come up.

Some specific duties and tasks include, but are not limited to, the following:

  • Provide consistent, high quality, compassionate care for laboratory animals in collaboration with the husbandry animal technicians.
  • Responsible for animal monitoring and health, behavior, and welfare surveillance, along with continuous awareness of current species-specific welfare issues in accordance with Canadian Council of Animal Care guidelines. This includes animal handling, inventories and record keeping, and communications if any abnormalities are observed.
  • Support the Translational Biology group with animal handling, restraints, injections, surgery, post-operative care, blood sampling and tissue collection.
  • Participate in lab maintenance, order, and receipt of needed supplies.
  • Maintain clear and accurate lab records (e.g., monitoring sheets, health reports, data spreadsheets).
  • Participate in the writing and execution of SOPs and animal protocols.
  • Execute other research tasks and provide research support as directed by the Manager or the Scientists.
  • Attend and participate in weekly meetings.
  • Complete additional responsibilities as assigned.

Qualifications:

  • Bachelor’s degree in relevant discipline and 1-3 years of experience with laboratory animals, or 0-3 years of related industrial experience, or an equivalent combination of education and experience.
  • Experience with rodent handling and in vivo experiments.
  • Experience with lab maintenance and lab records.
  • Ability to work safely in a laboratory environment.
  • Knowledge in laboratory animal standards and CCAC guidelines.
  • Experience with radiopharmaceuticals preferred, but not required.
  • Observational, organizational, data management and documentation skills.
  • A team-player with excellent interpersonal skills who is willing to make a real impact and accelerate the development of innovative target therapies in a fast-paced environment.

What’s in it for you:

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with employer matching.
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule:

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Administrative Assistant

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking an Administrative Assistant to join our Vancouver team. The ideal candidate will be a multi-tasker who will provide administrative support to our Vancouver staff, interact efficiently with our Boston office, and ensure that all Administrative Assistant duties and responsibilities are completed accurately and delivered with high quality, in a timely and professional manner. The role is responsible for handling day-to-day reception and administrative activities while maintaining a solid understanding of Company goals to ensure smooth execution of priorities.

Some specific duties and tasks include, but are not limited to, the following:

  • Provide receptionist and general administrative duties, including answering phones, managing the general email inbox, mail, and shipping, and receiving support.
  • Order, receive, and manage general office and kitchen supplies, restock of snacks & supplies, maintain kitchen appliances and partner with vendors for repairs.
  • Receive incoming delivery packages and routes to appropriate colleagues or teams, responsible for processing outgoing mailing and delivery requests.
  • Engage service vendors for office equipment maintenance, general office and housekeeping tasks and repairs.
  • Manage administrative needs of the Vancouver team including expense reports,
  • Book travel, and schedule internal and external meetings.
  • Aid in the coordination of company-wide events and projects, employee engagement activities, internal communications, new hire onboarding, and other companywide initiatives/projects as assigned.
  • Desk setup for new colleagues including basic office supplies and confirming receipt of office and IT equipment.
  • Handle confidential material and exercise discretion.

Qualifications:

  • High school diploma or equivalent completion of secondary education, Bachelor’s Degree preferred.
  • Two years’ administrative experience in an office environment where flexibility, prioritization and good interpersonal skills have been gained.
  • Strong organizational skills with the ability to multi-task
  • Proactive attitude and ability to thrive in a fast paced and dynamic environment.
  • Ability to work independently, multi-task, problem solve, and adjust priorities as competing projects vie for attention.
  • Ability to effectively collaborate with others to reach mutually agreeable outcomes and resolve potential conflicts.
  • Ability to build relationships at all levels of the organization.
  • MS Office skills including Word, Outlook, and Excel
  • Willingness and ability to learn new skills.

What’s in it for you:

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with employer matching.
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Senior Manager/Associate Director, Program Management, Clinical Operations

About Us:

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary:

Alpha-9 is seeking a Senior Manager/Associate Director of Program Management, Clinical Operations to lead program management activities for several early-stage radiopharmaceutical cancer therapeutics from IND-enabling studies through clinical trials. This role will ensure organizational alignment and oversee program execution, as well as foster team building and a collaborative environment and is responsible for working closely with team members to forecast key milestones and decision points and deliver program objectives.

Some specific duties and tasks include, but are not limited to, the following:

  • Lead cross-functional project teams to execute drug development projects from IND-enabling studies through early clinical trials.
  • Develop and maintain detailed project plans, timelines, and budgets, ensuring efficient resource allocation and adherence to project milestones.
  • Collaborate closely with key stakeholders, including R&D, Clinical Development, Clinical Operations and CMC Operations teams to align project goals and objectives.
  • Identify strategic decision points and facilitate cross-functional reviews to drive progress and consensus.
  • Monitor project progress and identify potential risks, proactively implementing mitigation strategies to ensure successful project outcomes.
  • Perform detailed reviews of study reports and regulatory filings to ensure accuracy and consistency.
  • Communicate project updates and status reports to senior management and relevant stakeholders.

Qualifications:

  • BS or advanced degree in a scientific discipline or related field.
  • Minimum of 8 years of clinical operations or related experience in the biotechnology or pharmaceutical industry.
  • Minimum of 3 years of experience in Project/Program Management within the biotechnology or pharmaceutical industry.
  • Proven track record of successfully managing complex projects from early-development stages through clinical proof of concept.
  • Strong understanding of clinical trial processes; previous experience with IND-enabling study requirements is a plus.
  • Strong experience in early-stage clinical trials and progressing them to later stages.
  • Excellent leadership and team management skills, with the ability to motivate and guide cross-functional teams.
  • Familiarity with domestic and international regulatory requirements (FDA, EMA, etc.) for drug development.
  • Demonstrated ability to influence others and negotiate, strong problem-solving abilities.
  • Exceptional communication skills, ability to build strong relationships at all levels of the organization.

What’s in it for you:

  • Competitive Salary, Bonus, and Equity
  • Medical, Dental and Vision Benefits
  • HSA and FSA available
  • Commuter Reimbursement
  • Retirement plan with employer match up to 3%
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Computational Scientist

About Us:

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking a Computational Scientist with proven track record of impacting drug discovery projects. The ideal candidate will have excellent knowledge and skills in a variety of computational tools and methodologies including docking, virtual screening, molecular dynamics, free energy perturbation, homology modeling, pharmacophore elucidation, and bioinformatics. Experience with target selection, small molecule and peptide drug discovery is a plus.

Some specific duties and tasks include, but are not limited to, the following:

  • Provide technical knowledge and input to project teams to drive decision making in target selection and drug discovery projects.
  • Identify and implement novel computational chemistry/science algorithms, technologies, and workflows.
  • Implement AI/machine learning approaches to enhance drug discovery efforts.
  • Establish strategies, develop workflows and cross-functional collaboration.
  • Provide coaching and mentoring to team members.
  • Routinely engage with Program Leads/Scientists to support and enable program progression in a timely manner.

Qualifications:

  • PhD in computational chemistry, bioinformatics, statistics, mathematics, computer science, computational biology, or a related field with 3+ years of relevant experience in pharma/biotech
  • Familiarity with state-of-the-art computational chemistry software, such as Schrödinger Suite, MOE, or similar tools
  • Proficient in at least one general purpose programming/data science languages including but not limited to R, Python, Julia
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you:

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with employer matching.
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Location: Vancouver, BC

To apply, use the form below.

Don’t see anything that matches your experience? Email us at careers@alpha9tx.com

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