We are seeking driven, creative, and entrepreneurial individuals to help shape our company. At Alpha-9, you’ll find a culture of collaboration, transparency, and innovation. We are passionate about developing new medicines to help people living with cancer, and we are looking to add to our growing team.

Open Positions

Senior Scientist, Radiochemistry

About Us

Alpha-9 Theranostics is a clinical stage, radiopharmaceutical company developing imaging and therapeutic molecules for solid and hematologic malignancies. We have multiple molecules that are headed into clinic within the next few years, and a robust pipeline of additional targets for future development. Using proprietary technology and the Company’s expertise, these differentiated molecules have the potential to meaningfully extend patients’ lives with favorable safety profiles. Alpha-9 was founded by researchers from the University of British Columbia and BC Cancer, with the goal of improving the lives of patients affected by metastatic cancers.

Position Summary

Alpha-9 is seeking a Senior Scientist, Radiochemistry to join our growing organization.  The ideal candidate will have experience developing radiolabeling, and analytical methods for targeted, peptide-based radiopharmaceuticals.  This person will be responsible for developing and delivering novel radiolabeled diagnostic and therapeutic compounds for both pre-clinical and clinical applications.

This position requires a high degree of collaboration, multi-tasking ability, and desire to strive in a fast-paced environment.  You will have the opportunity to contribute to the build-out and set-up of new laboratory facilities, interface with external partners, and mentor more junior staff.

Some specific duties and tasks include, but are not limited to, the following:

  • Develop radiolabeling and manufacturing methods for compounds with imaging and therapeutic applications
  • Work in multidisciplinary teams to define development project goals and timelines
  • Design and conduct radiochemistry experiments leading to robust radiolabeling processes and clinical formulations that meet target product profiles
  • Develop quality control procedures, analytical methods, and specifications for radiopharmaceuticals/API
  • Perform technology transfer of radiolabeling and analytical methods to third party CRO and CDMO partners
  • Support pre-clinical development by radiolabeling compounds for in vitro and in vivo evaluation
  • Troubleshoot, identify unusual results, and design experiments that establish root cause and/or enhance knowledge of the product being developed
  • Write necessary SOPs, development reports, test method protocols, batch records, and regulatory documentation
  • Set up and maintain automated chemistry modules and laboratory equipment
  • Conduct area radiation surveys, contamination control, and radioactive waste management
  • Demonstrate good safety practices and ensure radioprotection standards are upheld

Qualifications

  • PhD/MSc in Radiochemistry, Chemistry, Analytical Chemistry, Nuclear Engineering or equivalent knowledge or experience
  • 5+ years of experience with academic and/or commercial radiopharmaceutical development and production
  • Hands on experience in radiolabeling with radioisotopes used for imaging and therapeutic applications; experience with alpha emitters is a plus
  • Ability to plan and execute complex scientific projects
  • Understanding of regulatory requirements for development of radiopharmaceuticals
  • Demonstrated ability to troubleshoot, identify unusual results and design experiments that establish root cause
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with employer matching
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Senior Scientist, Research & Development

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking a Senior Scientist to drive discovery efforts for new targeted radiopharmaceutical products.  This person will be responsible for one or more discovery programs, including design and oversight of preclinical experiments leading to viable diagnostic and therapeutic clinical candidates.  The ideal candidate will have experience with radiopharmaceutical development.

We are an early-stage company, so this is a highly visible and impactful role in our growing organization. The ideal candidate will be a self-starter with the desire to collaborate cross-functionally and strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Lead discovery efforts for the development of targeted radiopharmaceuticals
  • Design and oversee preclinical experiments to demonstrate in vitroactivities and in vivo efficacy as well as to define mechanism of action
  • Manage external teams (CROs and academic collaboration) to deliver peptides/peptidomimetics or small molecule-based radiopharmaceutical therapeutics (RPTs) for biological evaluation
  • Matrixed management of scientists and research associates conducting peptide synthesis, biological assays and preclinical studies
  • Interpret and analyze data, prepare, and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Drive key go/no-go decision making
  • Collaborate with CMC and clinical teams for IND filings
  • Represent company at scientific conferences including preparation of data for presentation

Qualifications

  • A PhD in cancer biology, cell or molecular biology, genetics, radiochemistry, medicinal chemistry or a related discipline with relevant post-doctoral training and a proventrack record of scientific excellence and creativity
  • 5+ years of experience in cancer research and drug discovery in biotech or pharmaceutical industries; alternatively, candidates with significant relevant academic research experience will be considered
  • Expertise in cellular and molecular biology techniques, in vitro/in vivomodels for target validation and drug efficacy studies, medicinal chemistry, peptide synthesis, structure-based drug design, and/or synthetic organic chemistry
  • Experience in leading drug discovery projects/program management preferred, but not required
  • Experience in radiopharmaceutical development preferred, but not required
  • Attention to detail with excellent organizational skills, verbal communication and writing skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies

What’s in it for you

  • Competitive compensation, health and welfare and time off benefits
  • Flexible work environment
  • 20 vacation days, 17 holidays, 5 paid sick days per year
  • Extended health benefits
  • Retirement match
  • Commuter benefits

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Research & Development Chemist

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking a Chemist to join our growing organization.  The ideal candidate will have experience with solid-phase peptide synthesis, and preferably with radiopharmaceutical development.  This person will be responsible for designing, planning and synthesizing peptides/peptidomimetic building blocks and precursors for radiopharmaceutical product candidates.

We are an early stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Design, plan, and synthesize peptides/peptidomimetics or small molecule-based building blocks and drug substances for radiopharmaceutical development
  • Support senior chemists in analytical development and validation using LC-MS/MS, GC-MS, HPLC and NMR
  • Work with internal/external teams to deliver compounds for biological evaluation
  • Maintain clear and accurate lab records
  • Interpret and analyze data, prepare, and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Participate in the writing and execution of patent applications
  • Contribute to build-out and set up of a new laboratory facility
  • Lab maintenance and support of ordering and receipt of needed supplies

Qualifications

  • BS or MS degree in Chemistry or related area; and 0 to 5+ years of related industrial experience
  • Solid understanding and practical experience in synthetic organic methodology and chemical process research, combined with strong problem-solving skills
  • Experience in modern synthetic and analytical techniques
  • Experience with solid-phase peptide synthesis preferred, but not required
  • Experience in radiopharmaceutical development preferred, but not required
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Competitive compensation, health and welfare and time off benefits
  • 20 vacation days, 17 holidays, 5 paid sick days per year
  • Extended health benefits
  • Retirement match
  • Commuter benefits

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Research & Development Chemist III

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking an experienced Chemist to join our growing organization.  The ideal candidate will have significant experience with solid-phase peptide synthesis, and preferably with radiopharmaceutical development.  This person will be responsible for designing, planning, and synthesizing peptides/peptidomimetic building blocks and precursors for radiopharmaceutical product candidates and mentoring other chemists.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Design, plan, and synthesize peptides/peptidomimetics or small molecule-based building blocks and drug substances for radiopharmaceutical development
  • Analytical development and validation using LC-MS/MS, GC-MS, HPLC and NMR
  • Partner and collaborate with internal/external teams to deliver compounds for biological evaluation
  • Maintain clear and accurate lab records
  • Interpret and analyze data, prepare, and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Key participant in the writing and execution of patent applications
  • Contribute to build-out and set up of a new laboratory facility
  • Mentor Chemists I and II
  • Lab maintenance and support of ordering and receipt of needed supplies

Qualifications

  • MS or Ph.D. degree in Chemistry or related area; and 5+ years of related industrial experience
  • Solid understanding and practical experience in synthetic organic methodology and chemical process research, combined with strong problem-solving skills
  • Significant experience in modern synthetic and analytical techniques
  • Significant experience with solid-phase peptide synthesis preferred, but not required
  • Significant experience in radiopharmaceutical development preferred, but not required
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Competitive compensation, health and welfare and time off benefits
  • 20 vacation days, 17 holidays, 5 paid sick days per year
  • Extended health benefits
  • Retirement match
  • Commuter benefits

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Associate Scientist, Medicinal Chemistry & Radiochemistry

About Us

Alpha-9 Theranostics is a clinical stage, radiopharmaceutical company developing imaging and therapeutic molecules for solid and hematologic malignancies. We have multiple molecules that are headed into clinic within the next few years, and a robust pipeline of additional targets for future development. Using proprietary technology and the Company’s expertise, these differentiated molecules have the potential to meaningfully extend patients’ lives with favorable safety profiles. Alpha-9 was founded by researchers from the University of British Columbia and BC Cancer, with the goal of improving the lives of patients affected by metastatic cancers.

Position Description

Alpha-9 is seeking Associate Scientists to join our Medicinal Chemistry/Radiochemistry group.  The ideal candidate will have hands-on experience in synthetic organic chemistry, including in the synthesis, isolation and purification of either small molecules, peptides or peptidomimetics. This person will be responsible synthesizing peptides/peptidomimetic building blocks and precursors for radiopharmaceutical product candidates. Experience with solid-phase peptide synthesis and radiolabeling in the discovery setting is a plus, but training would be provided if needed.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Synthesis of peptides/peptidomimetics or small molecule-based building blocks and drug substances for radiopharmaceutical development
  • Compound characterization employing LC-MS/MS, GC-MS, HPLC and NMR
  • Active participation in discussions and present results in team meetings
  • Key participant in the writing of patent applications
  • Contribution to build-out and set up of a new laboratory facility
  • Maintenance of clear and accurate lab records, adherence to all safety and compliance requirements
  • Lab maintenance and support of ordering and receipt of needed supplies

Qualifications

  • BS or MS. degree in Chemistry or related area with 2-5+ years of related industrial experience
  • Solid understanding and practical experience in synthetic organic chemistry
  • Solid experience in modern synthetic and analytical techniques
  • Experience with solid-phase peptide synthesis preferred, but not required
  • Experience in radiopharmaceutical discovery preferred, but not required
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with employer matching.
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Chemistry Program Lead, Research & Development

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking a Program Lead to drive discovery efforts for new targeted radiopharmaceutical products.  This person will be responsible for one or more discovery programs, including design and oversight of preclinical experiments leading to viable diagnostic and therapeutic clinical candidates.  The ideal candidate will have experience with moving a small molecule, peptide or peptidomimetic through the discovery stages to clinical candidate selection. Radiopharmaceutical experience is a plus, but not required.

We are an early-stage company, so this is a highly visible and impactful role in our growing organization. The ideal candidate will be a self-starter with the desire to collaborate cross-functionally and strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Lead discovery efforts for the development of targeted radiopharmaceuticals
  • Manage external teams (CROs and academic collaborations) to deliver peptides/peptidomimetics or small molecule-based radiopharmaceuticals (RPs) for biological evaluation
  • Work closely with internal groups to design and oversee preclinical experiments to demonstrate in vitrocharacteristics and in vivo PK/efficacy as well as to define mechanism of action
  • Matrixed management of scientists and research associates conducting peptide synthesis, biological assays and preclinical studies
  • Interpret and analyze data, prepare, and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Drive key go/no-go decision making
  • Collaborate with CMC and clinical teams for IND filings
  • Represent company at scientific conferences including preparation of data for presentation

Qualifications

  • A PhD in chemistry, medicinal chemistry or radiochemistry, with relevant post-doctoral training and a proventrack record of scientific excellence and creativity
  • 5+ years of experience in drug discovery research in biotech or pharmaceutical industries; alternatively, candidates with significant relevant academic research experience will be considered
  • Expertise in medicinal chemistry, small molecule and/or peptide synthesis, and structure-based drug design
  • Experience in leading drug discovery projects to reach key discovery milestones
  • Experience in radiopharmaceutical development preferred, but not required
  • Attention to detail with excellent organizational skills, verbal communication and writing skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with employer matching.
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Biology Program Lead, Research & Development

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking a Program Lead to drive discovery efforts for new targeted radiopharmaceutical products.  This person will be responsible for one or more discovery programs, including design and oversight of preclinical experiments leading to viable diagnostic and therapeutic clinical candidates. The ideal candidate will have experience with moving a small molecule, peptide or peptidomimetic through the discovery stages to clinical candidate selection. Radiopharmaceutical experience is a plus, but not required.

We are an early-stage company, so this is a highly visible and impactful role in our growing organization. The ideal candidate will be a self-starter with the desire to collaborate cross-functionally and strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Lead discovery efforts for the development of targeted radiopharmaceuticals
  • Design and oversee preclinical experiments to demonstrate in vitrocharacteristics and in vivo PK/efficacy as well as to define mechanism of action
  • Manage external teams (CROs and academic collaborations) to deliver peptides/peptidomimetics or small molecule-based radiopharmaceuticals (RPs) for biological evaluation
  • Matrixed management of scientists and research associates conducting peptide synthesis, biological assays and preclinical studies
  • Interpret and analyze data, prepare, and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Drive key go/no-go decision making
  • Collaborate with CMC and clinical teams for IND filings
  • Represent company at scientific conferences including preparation of data for presentation

Qualifications

  • A PhD in cancer biology, cell or molecular biology, Immunology, Biochemistry, and/or Pharmacology with relevant post-doctoral training and a proven track record of scientific excellence and creativity
  • 5+ years of experience in oncology drug discovery in biotech or pharmaceutical industries; alternatively, candidates with significant relevant academic research experience will be considered
  • Expertise in cellular and molecular biology techniques, in vitro/in vivo models for target validation, PK evaluation, and drug efficacy studies
  • Experience in leading drug discovery projects to reach key discovery milestones
  • Experience in radiopharmaceutical development preferred, but not required
  • Attention to detail with excellent organizational skills, verbal communication and writing skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary, Bonus, and Equity
  • Commuter Reimbursement
  • Group Registered Retirement Savings Plan with employer matching.
  • 20 vacation days
  • 17 Holidays
  • 5 Sick Days
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Associate Director/Director, Biology

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking an Associate Director/Director lead our Biology group. The ideal candidate will have a proven track record of effectively leading a biology group to reach discovery milestones, with excellent knowledge and skills in Cancer, Molecular/Cell Biology, Biochemistry, and/or Pharmacology. The candidate will have experience with moving a small molecule, peptide or peptidomimetic through the discovery stages to clinical candidate selection. Experience with radiopharmaceuticals is a plus.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Lead the biology efforts towards the discovery and development of radiopharmaceuticals
  • Establish strategies, develop workflows and cross-functional collaborations, integrate new technologies
  • Provide coaching and mentoring to team members
  • Routinely engage with Program Leads to support and enable program progression in a timely manner
  • Manage and direct the activities of Scientists and Associate Scientists
  • Engage and manage CROs and academic collaboration
  • Design and execute preclinical experiments to demonstrate in vitro activities and in vivo efficacy as well as to define mechanism of action
  • Interpret and analyze data, prepare and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Contribute to IND submissions

Qualifications

  • A PhD in Cancer, Cell or Molecular Biology, Biochemistry, and/or Pharmacology with 8+ years of relevant post-doctoral training and/or industrial experience and a proven track record of scientific excellence and creativity
  • Proven track record of effectively leading a biology group to reach discovery milestones
  • Expertise in the development, optimization and execution of assays to establish MoA, binding affinity, selectivity and potency
  • Experience in radiopharmaceutical discovery preferred, but not required
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary
  • Bonus and equity eligibility
  • Flexible work environment
  • 20 vacation days
  • 18 Holidays
  • Group Registered Retirement Savings Plan with 5% employer match
  • Commuter reimbursement
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Associate Director/Director, Chemistry

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking an Associate Director/Director to lead our Chemistry group. The ideal candidate will have a proven track record of effectively leading a chemistry group to reach discovery milestones, with excellent knowledge and skills in synthetic chemistry, medicinal chemistry, and drug discovery. Experience with radiopharmaceuticals is a plus.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Lead the chemistry and radiochemistry efforts towards the discovery and development of radiopharmaceuticals
  • Establish strategies, develop workflows and cross-functional collaborations, integrate new technologies
  • Provide coaching and mentoring to team members
  • Routinely engage with Program Leads to support and enable program progression in a timely manner
  • Manage and direct the activities of Scientists and Associate Scientists
  • Engage and manage CROs and academic collaboration
  • Develop SAR correlations and design compounds with optimized profiles
  • Design formulation studies to enable in vivo studies and CMC transitions
  • Interpret and analyze data, prepare and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Contribute to IND submissions

Qualifications

  • A PhD in chemistry, medicinal chemistry, or radiochemistry with 8+ years of relevant post-doctoral training and/or industrial experience and a proven track record of scientific excellence and creativity
  • Proven track record of effectively leading a chemistry group to reach discovery milestones
  • Expertise in medicinal chemistry, small molecule and/or peptide synthesis, and structure-based drug design
  • Experience in radiopharmaceutical development preferred, but not required
  • Attention to detail with excellent organizational skills, verbal communication and writing skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary
  • Bonus and equity eligibility
  • Flexible work environment
  • 20 vacation days
  • 18 Holidays
  • Group Registered Retirement Savings Plan with 5% employer match
  • Commuter reimbursement
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Associate Scientist, Biology

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking Associate Scientists to join our Biology group.  The ideal candidate will have hands-on experience and skills in Molecular/Cell Biology, Biochemistry, and/or Pharmacology. Experience with radiopharmaceuticals is a plus, but training would be provided if needed.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to thrive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Aid in the validation of pipeline targets
  • Contribute to the design, validation and execution of preclinical experiments to demonstrate in vitro activities and in vivo efficacy, as well as define mechanism of action of drug candidates
  • Contribute to data analysis and report experimental results to project teams
  • Contribution to build-out and set up of a new laboratory facility
  • Maintenance of clear and accurate lab records, adherence to all safety and compliance requirements

Qualifications

  • BS or MS. degree in Cell/Molecular biology or related area with 2-5+ years of related industrial experience
  • Solid understanding of and hands-on experience in the development, optimization and execution of assays to establish MoA, binding affinity, selectivity and potency
  • Experience in radiopharmaceutical discovery preferred, but not required
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary
  • Bonus and equity eligibility
  • Flexible work environment
  • 20 vacation days
  • 18 Holidays
  • Group Registered Retirement Savings Plan with 5% employer match
  • Commuter reimbursement
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Scientist, Biology

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking Scientists to join our Biology group.  The ideal candidate will have excellent knowledge and skills in Cancer/Molecular/Cell Biology, Biochemistry, and/or Pharmacology to support our discovery programs. Experience with radiopharmaceuticals is a plus.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to thrive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Design and carry out experiments to validate pipeline targets
  • Design, validate and execute preclinical experiments to demonstrate in vitro activities and in vivo efficacy, as well as define mechanism of action of drug candidates
  • Contribute to strategic plans and assays development
  • Interpret and analyze data, prepare, and review study reports, communicate project progress to internal stakeholders and external collaborators
  • Supervise and mentor Associate Scientists
  • Contribute to build-out and set up of a new laboratory facility
  • Maintain clear and accurate lab records, adhere to all safety and compliance requirements

Qualifications

  • A PhD in Cancer, Cell or Molecular Biology, Biochemistry, and/or Pharmacology with 2-5+ years of relevant post-doctoral training or industrial experience and a proven track record of scientific excellence and creativity
  • Expertise in the development, optimization and execution of assays to establish MoA, binding affinity, selectivity and potency
  • Experience in radiopharmaceutical discovery preferred, but not required
  • Excellent observational, organizational, data management, and documentation skills
  • A team player with excellent interpersonal skills and a strong passion for the discovery of targeted therapies in a fast-paced start-up environment

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary
  • Bonus and equity eligibility
  • Flexible work environment
  • 20 vacation days
  • 18 Holidays
  • Group Registered Retirement Savings Plan with 5% employer match
  • Commuter reimbursement
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

Senior Scientist, Chemistry, Peptides

About Us

Alpha-9 Theranostics is a clinical-stage biotechnology company developing radiopharmaceuticals that image and treat solid and hematologic malignancies. Alpha-9 has a portfolio of molecules entering clinical trials and a robust pipeline of additional targets for future development. Building on years of radiopharmaceutical expertise and with backing from leading healthcare investors, Alpha-9 is committed to developing novel radiopharmaceuticals that meaningfully extend patients’ lives.

Position Summary

Alpha-9 is seeking Senior Scientists to join our Chemistry group.  The ideal candidate will have hands-on experience in synthetic organic chemistry, including in the synthesis, isolation and purification of either small molecules, peptides or peptidomimetics. This person will be responsible for synthesizing peptides/peptidomimetic building blocks and precursors for radiopharmaceutical product candidates. Expertise in solid-phase peptide synthesis and the optimization of peptide ligands required.

We are an early-stage company, so you will have the opportunity to participate cross-functionally and contribute to the build-out and set-up of new laboratory facilities.  The ideal candidate will have multi-tasking ability and a desire to strive in a fast-paced environment.

Some specific duties and tasks include, but are not limited to, the following:

  • Design and synthesis of peptides/peptidomimetics or small molecule-based building blocks and drug substances for radiopharmaceutical development
  • Working closely cross-functionally to achieve project goals
  • Supervision and mentoring of junior scientists
  • Compound characterization employing LC-MS/MS, GC-MS, HPLC and NMR
  • Lead project discussions and present results in team meetings
  • Key participant in the writing of patent applications
  • Maintenance of clear and accurate lab records, adherence to all safety and compliance requirements

Qualifications

  • PhD in Chemistry or related area with 5+ years of relevant industrial drug discovery experience
  • Solid understanding and practical experience in peptide drug discovery
  • Solid experience in modern synthetic and analytical techniques
  • Excellent observational, organizational, data management, and documentation skills

What’s in it for you

  • Full extended health and dental benefits
  • Competitive Salary
  • Bonus and equity eligibility
  • Flexible work environment
  • 20 vacation days
  • 18 Holidays
  • Group Registered Retirement Savings Plan with 5% employer match
  • Commuter reimbursement
  • Long Term Disability
  • Life Insurance
  • Impactful rewarding work

Schedule

  • Full Time Permanent

Location: Vancouver

Timing: ASAP

To apply, use the form below.

Don’t see anything that matches your experience? Email us at careers@alpha9tx.com

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